Comprehensive 3D Model of Shock Wave-Brain Interactions in Blast-Induced Traumatic Brain Injuries PRINCIPAL INVESTIGATOR:
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منابع مشابه
Biomechanical analysis of blast-induced traumatic brain injury
Purpose: Blast-induced traumatic brain injury (bTBI) is one of the causes of death or permanent invalidity which can occur unexpectedly in both military and civilian populations. This study set out to conduct a combined Eulerian-Lagrangian computational analysis of the interaction between a single planar blast wave and a human head in order to assess the extent of intracranial shock w...
متن کاملMechanics of blast loading on the head models in the study of traumatic brain injury using experimental and computational approaches.
Blast waves generated by improvised explosive devices can cause mild, moderate to severe traumatic brain injury in soldiers and civilians. To understand the interactions of blast waves on the head and brain and to identify the mechanisms of injury, compression-driven air shock tubes are extensively used in laboratory settings to simulate the field conditions. The overall goal of this effort is ...
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The prevalence of blast induced traumatic brain injury in conflicts in Iraq and Afghanistan has motivated laboratory scale experiments on biomedical effects of blast waves and studies of blast wave transmission properties of various materials in hopes of improving armor design to mitigate these injuries. This paper describes the design and performance of a table-top shock tube that is more conv...
متن کاملThe Effect of Shock Wave on a Human Head
When a pressure wave of finite amplitude is generated in air by a rapid release of energy, such as high-pressure gas storage vessel or the blast from dynamite, there may be undetected brain injuries even though protective armors prevent the penetration of the projectile. To study brain tissue injury and design a better personnel head armor under blast wave, computational models of human head ha...
متن کاملBlast-Associated Shock Waves Result in Increased Brain Vascular Leakage and Elevated ROS Levels in a Rat Model of Traumatic Brain Injury
Blast-associated shock wave-induced traumatic brain injury (bTBI) remains a persistent risk for armed forces worldwide, yet its detailed pathophysiology remains to be fully investigated. In this study, we have designed and characterized a laboratory-scale shock tube to develop a rodent model of bTBI. Our blast tube, driven by a mixture of oxygen and acetylene, effectively generates blast overpr...
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تاریخ انتشار 2010